Cock Bombs

What is Cock Bombs?

What it is A co-formulation of two phosphodiesterase type-5 (PDE5) inhibitors: sildenafil (shorter-acting) and tadalafil (longer-acting). Both increase intracellular cGMP in smooth muscle by inhibiting PDE5, a key enzyme in nitric-oxide signaling. Rationale (laboratory/clinical-research context) Because the agents have different pharmacokinetics—sildenafil’s terminal half-life is ~4 hours, tadalafil’s is ~17.5 hours—a combination is hypothesized to merge faster onset/shorter duration effects with prolonged activity.

Volume: 100ct